How Are The PEOs Delivered to Your Tissue?

DHARemember that there are few “free” fatty acids in your bloodstream and they are bound to albumin or apolipoproteins. These apolipoproteins are proteins that blind lipids to form lipoproteins. Lipoprotein lipase is found in the inner lining of all blood vessels and allows splitting of the PEOs and all the fatty acids (Parent omega 6 and parent omega 3 fatty acids) for incorporation into tissues. These fatty acids (Parent omega 6 and parent omega 3 fatty acids) can naturally pass through cell membranes (if the membrane is unadulterated), but they can move faster with the help of the proteins which are termed “fatty acid transport proteins (FATPs). Fatty acid binding proteins (FABPs) are inside the cell and act as a magnet expediting the travel of fatty acids from outside to inside the cell.

“Influence of omega-3 fatty acids on the prostaglandin-metabolism in healthy volunteers … synergistic effect of omega 6 and omega 3 fatty acids at low doses which are greater than the effect of high doses of omega 3 fatty acids alone.” Prostaglandins in the Cardiovascular System, 1992.

Acylation stimulating proteins (ASPs) within the cells stimulate incorporation of fatty acids into more complex structures. In the brain, a key EFA-related enzyme is particularly phospholipase, PLA influencing critical arachidonic acid (AA). DHA is important to brain structure, but for brain growth AA is #1 via conversion to LTCA.

Furthermore, as demonstrated in Dr. Campbell’s seminal article, “Abdominal fatty acid composition and impaired oxygen supply in cystic fibrosis patients,” the Parent omega 6’s oxygen in the cell membrane can reversibly disassociate (release) providing increased cellular oxygen at physiologic pressure close to hemoglobin’s. The oxygen can come from the cell membrane, itself in addition to the blood stream, as Dr. Campbell’s work clearly demonstrated.


Mike Maunu – Founder